Background: Menopause is a natural process for women and is a universal event. Perimenopause is the transition period of a woman's life shortly before the occurrence and around menopause. During this period, women may experience physical and psychological problems due to the changes in the level of estrogen and progesterone, which may affect their quality of life.

Objective: The study aimed to assess the menopause-specific symptoms and quality of life of perimenopausal women.

Materials and Methods: Non-experimental cross-sectional research design was adopted with 60 participants selected by convenience sampling technique at the selected village. The tool used for the study was demographic variables and the Menopause Specific Quality of Life Questionnaire to assess the quality of life. The interview method was to collect the data on one to one basis.

Results: Out of 60 participants, 25(41.67%) had poor quality of life, 34(56.7%) had moderate, and only one (1.67%) had a good quality of life. The severity of menopause-related symptoms is found in all physical, psychosocial, vasomotor, and sexual domains. Demographic variable flow type had shown a statistically significant association with the quality of life of perimenopausal women at p<0.05.

Conclusion: The present study findings revealed that most perimenopausal women experienced moderate to poor quality of life. Nurses play a vital role in assess the symptoms and designing the nursing intervention to alleviate the symptoms associated with menopause and improve the quality of life.