A quasi experimental design with pre and post-test without control group was undertaken on 50 post natal mothers who were selected by purposive sampling technique from postnatal ward in K.D.J Hospital, Gwalior to assess the effectiveness of SIM regarding prevention of puerperal sepsis on knowledge related to practice of the post natal mothers and the data were collected by using closed ended questionnaire.

Demographic findings revealed that majority of the postnatal mothers were between the age group of 21-25 years (66%) residing at rural area (62%). Most (86%) of them were Hindus, 28% of them had high school education, 56% belonged to joint family, 36% belonged to the income group of > Rs. 3000 and 52% of them had one child.

The findings shows that the mean knowledge scores on practice in pre-test (13.54 ± 7.10) which is 35.63% whereas, in post-test mean score (28.82 ± 6.01) which is 75.84% reveals 40.21% enhancement of knowledge score on practice. Area wise post-test knowledge scores on practice shows that highest mean score (0.88 ± 0.33) which is 88% was obtained for “complication of puerperal sepsis” which was also highest (46%) during pre-test and the lowest and the post-test mean score (1.98 ± 0.98) which is 66% was obtained for the area “factors related to puerperal sepsis” whereas, in pretest the lowest mean score (0.56 ± 0.76) was obtained for the area “meaning of puerperium” which is 28%. O-give curve showing rapid increase in scores from the lowest to the highest during post-test which was higher when compared to pre-test score.

Highly significant (p< 0.01) difference was found between pre and post-test knowledge scores related to practice of puerperal sepsis and no significant association between knowledge scores related to practice scores of mothers with demographic variables except occupation and type of family (p< 0.05).