P-ISSN: 2664-2298, E-ISSN: 2664-2301
Printed Journal | Refereed Journal | Peer Reviewed Journal
International Journal of Obstetrics and Gynaecological Nursing
2024, Vol. 6, Issue 2, Part C
Adipocytokines as a fertility factor: A connection between obesity and PCOS (Polycystic Ovary Syndrome)
Rana Hasan Ahmed
Background: Obesity is a pandemic that is still growing and is linked to metabolic, androgenic, and reproductive comorbidities in women. A complex endocrinopathy, polycystic ovarian syndrome (PCOS) is characterized by hyperandrogenic, reproductive, and metabolic dysfunctional characteristics. PCOS and obesity frequently coexist. The metabolic syndrome that is linked to PCOS and its clinicopathological symptoms are mostly caused by insulin resistance and the hyperinsulinemia that follows.
Objective: This study's main goal was to assess the amounts of the proteins leptin, resistin, retinol binding protein-4, and chemerin in people with PCOS.
Methods: The study was conducted from March 1st, 2024, to June 30th, 2024, at Tikit Teaching Hospital. There were 150 female patients in the trial, ranging in age from 15 to 45. following the completion of clinical and medical examinations by a physician who specializes in this area. In addition to selecting a random group, 75 samples of healthy females in the same age range as the control group were included.
Results: The ill groups had considerably greater blood concentrations of Leptin, Resistin, Retinol binding protein-4, and Chemerin (p<0.01) compared to the healthy individuals (C).
Conclusion: Obesity is far more common in PCOS patients, and it is a significant and separate cause of PCOS. Because adipokines allow adipose tissue to communicate with the brain, ovaries, and uterus, this tissue is concerned with the regulation of the law in the metabolic homes of women who have PCOS. According to the data above, adipokines are most likely implicated in the development of PCOS.
Pages : 184-192 | 81 Views | 38 Downloads
How to cite this article:
Rana Hasan Ahmed. Adipocytokines as a fertility factor: A connection between obesity and PCOS (Polycystic Ovary Syndrome). Int J Obstetrics Gynaecological Nurs 2024;6(2):184-192. DOI: 10.33545/26642298.2024.v6.i2c.175
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